Quantitative Analysis of Biochemistry

Course Description: This course focuses on research related to the discovery and development of therapeutic agents. Key topics include drug structure, mechanisms of action, and drug delivery, all of which are covered in detail. By the end of the course, students will develop a solid understanding of the structures and mechanisms of major classes of drugs, including both small-molecule therapeutics and biologics; the structures and reactivity of amino acids, proteins, nucleic acids, carbohydrates, fatty acids, enzyme cofactors, and other biomolecules; nomenclature, structure, and chemical reactivity of organic molecules; and the methods used to elucidate the structures of biological macromolecules and low-molecular-weight organic compounds. Comprehensive exploration of modern drug discovery from chemical and biological perspectives. Covers molecular mechanisms, protein structures, enzymology, and pharmaceutical development.

Assessment Methods: Recommendation Letter Opportunities, Research Papers

Ideal Students

Students fascinated by how scientists discover new medicines to fight infections. • Potential Topic: Investigate how penicillin was discovered and explore modern high-throughput screening methods for identifying new antibiotic candidates. Students concerned about the global antibiotic resistance crisis and its solutions. • Potential Topic: Analyze the mechanisms by which bacteria develop resistance to drugs like methicillin, and propose chemical modifications to existing antibiotics to overcome resistance. Students aiming to pioneer next-generation therapeutics for drug-resistant diseases. • Potential Topic: Design a novel antibiotic using structure-based drug design targeting tuberculosis, incorporating mechanisms to prevent resistance development and evaluating pharmacokinetic properties.

Potential Research Topics

Biochemistry, Biology, Chemistry | Biochemistry, Drug Discovery, Laboratory Skills, Organic Chemistry, Protein Engineering, Research Methods

Online (Remote)

Applications are reviewed for research readiness and fit. A place is confirmed only after an admissions decision.